L-ABRINE b
CAS No. 526-31-8
L-ABRINE b ( L-(+)-Abrine | L-N-Methyltryptophan | N-α-Methyl-L-tryptophan )
产品货号. M20460 CAS No. 526-31-8
L-ABRINE 是在 jequirity 种子中发现的一种有毒蛋白质。可用作相思豆暴露的生物标志物。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 50MG | ¥340 | 有现货 |
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| 100MG | ¥535 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称L-ABRINE b
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述L-ABRINE 是在 jequirity 种子中发现的一种有毒蛋白质。可用作相思豆暴露的生物标志物。
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产品描述L-ABRINE is a toxic protein found in the jequirity seed.can be used as a biomarker for abrin exposure.
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体外实验L-(+)-Abrine is a marker for abrin poisoning. A strong indication for abrin poisoning is the presence of the chemical maker L-(+)-Abrine, which can survive metabolism in significant amounts making it detectable in human urine.
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体内实验Abrin is a toxic protein found in the jequirity seed. L-(+)-Abrine (L-Abrine) is also found in the jequirity seed and can be used as a biomarker for abrin exposure. An animal study is designed to monitor the excretion and recovery of L-(+)-Abrine in 20 rats. The animals are exposed to one of three concentrations of L-(+)-Abrine, a single high concentration of L-tryptophan, or no agent (control). The low L-(+)-Abrine dose corresponds to 0.63 LD50 i.p. abrin in mice, assuming a concentration ratio of 1:4 of abrin to L-(+)-Abrine and an LD50 for abrin of 20 μg/kg. The mid and high L-(+)-Abrine (250 and 400 μg/kg) doses are included to ensure that the target analyte can be detected and tracked over the course of the experiment.
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同义词L-(+)-Abrine | L-N-Methyltryptophan | N-α-Methyl-L-tryptophan
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通路Others
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靶点Other Targets
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受体Others
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研究领域——
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适应症——
化学信息
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CAS Number526-31-8
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分子量218.25
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分子式C12H14N2O2
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纯度>98% (HPLC)
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溶解度DMSO:2 mg/mL (9.16 mM)
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SMILESCN[C@@H](Cc1c[nH]c2ccccc12)C(O)=O
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化学全称N-Methyl-L-tryptophan
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Johnson R C Zhou Y Jain R et al. Quantification of L-Abrine in Human and Rat Urine: A Biomarker for the Toxin Abrin[J]. Journal of Analytical Toxicology 2009 33(2):77-84.
产品手册
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